Showing posts with label cancer vaccine. Show all posts
Showing posts with label cancer vaccine. Show all posts

Tuesday, September 7, 2010

Pfizer's Decision Leaves Celldex Reeling

Apparently the cancer vaccine honeymoon is over. Despite what looked like promising early-stage clinical data, Pfizer (NYSE:PFE) has decided to end its collaboration with Celldex Therapeutics (Nasdaq:CLDX) for the anti-cancer immunotherapeutic CDX-110.

While it is not unusual for small oncology-focused biotechs to trade down after the annual ASCO meeting - the most important oncology-related medical conference on the calendar - Celldex has done a bit worse than most. There had been fears that Pfizer's commitment was something less than complete, but Friday's announcement walloped Celldex's stock.  

Where Does Celldex Go From Here?
Celldex is putting on a brave face for its shareholders. The company is vowing to continue developing the product on its own, presumably with an eye toward striking another deal with a larger pharmaceutical company somewhere down the road. Sometimes this works out - there are examples where a partner has dropped out and the drug still ultimately makes it to market. Unfortunately, companies like GenVec (Nasdaq:GNVC), Trubion (Nasdaq:TRBN) and Neurocrine Biosciences (Nasdaq:NBIX) have all found that the loss of Pfizer as a partner is not a good sign for the drug involved.
 

To read the full piece, please go to:
http://stocks.investopedia.com/stock-analysis/2010/Pfizers-Decision-Leaves-Celldex-Reeling-PFE-CLDX-GNVC-TRBN-NBIX0907.aspx

Wednesday, July 7, 2010

Cancer Vaccines Continue To Show Promise

I have to applaud the patience and diligence of the folks running Dendreon (Nasdaq:DNDN). After years of setbacks and complications (including three Phase 3 studies), the company and its investors finally saw the big payoff as the FDA approved the first-ever cancer vaccine - Provenge. 

With Provenge now on the market, and the squabbling and speculating about reimbursement fully underway, the question moves to who might be next to advance a cancer vaccine to the market. Is this really a major new avenue of oncology, or is it a small access road along the bigger highway of traditional drugs? 


For the complete column, please go to:
http://stocks.investopedia.com/stock-analysis/2010/Cancer-Vaccines-Continue-To-Show-Promise-DNDN-SNY-GSK-VICL-CLDX-PFE-GERN0707.aspx