Thursday, November 28, 2019

Lexicon Waiting For Clarity On Its Diabetes Franchise

Lexicon Pharmaceuticals (LXRX) is now in a “hurry up and wait” limbo, as the company waits for clarity on its dispute resolution petition with the FDA regarding Zynquista in Type 1 diabetes and as investors wait for more information and clarity on the clinical profile of Zynquista in Type 2 diabetes and Lexicon’s efforts to re-partner the drug.

For now, I believe $4/share is still a pretty fair value for Lexicon shares. A manageable path to approval of Zynquista in Type 1 diabetes would be a significant value-driver for the shares, as would any improvement in the apparent clinical profile of the drug in Type 2 diabetes. Favorable data from the Xermelo biliary tract cancer study or LX9211 in pain would likewise be positives.

Said differently, there are a lot of things that could go right (and go right relatively quickly) for Lexicon and drive a much higher share price, but I believe shareholders need to go in with their eyes open to the downside risk if those favorable outcomes don’t develop.

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Lexicon Waiting For Clarity On Its Diabetes Franchise

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